Estimates of causal mediation in the relationship between hospital-diagnosed prenatal infection(s) and having one or more developmental concern(s) identified at age 6–8 weeks or age 27–30 months child health reviews
| Mediator variable | Total effect (β) | Average direct effect (β) | Average causal mediated effect (β) | % of total effect mediated |
| Low birth weight | 0.046 (0.031 to 0.063) | 0.043 (0.029 to 0.060) | 0.002 (0.001 to 0.003) | 5.18% (3.77% to 7.65%) |
| Preterm birth | 0.046 (0.031 to 0.0.063) | 0.042 (0.028 to 0.059) | 0.003 (0.002 to 0.004) | 7.37% (5.36% to 10.88%) |
β refers to beta-coefficient. 95% CIs are shown in parentheses underneath estimates. Models adjust for sex of child, area-based deprivation, maternal age, maternal prenatal smoking and maternal history of mental health hospital admission(s).